Female sexual health testing: STI screening and HPV explained

BPR Clinic20 October 20265 min readLer em português

Many sexually transmitted infections cause no symptoms. Here is what the Female Sexual Health Advanced Screen and the HPV test check, and how they relate to cervical screening.

Tests in this article:Female Sexual Health - Advanced Screen,HPV (HR mRNA types 16, 18 + others)

A new relationship. A partner who mentions a past infection. Or simply the sense that it has been a while since the last check. Sexual health testing is a routine part of looking after yourself, and it is often done when nothing feels wrong at all. That is the point: many sexually transmitted infections (STIs) do not cause symptoms. This guide explains what the female sexual health tests in the BPR catalogue check, and how HPV testing fits alongside NHS cervical screening.

Why testing without symptoms matters

The NHS notes that many STIs have no symptoms, so you can have one without knowing, and that the only way to know for sure is to get tested (NHS, STIs). A 2022 review in JAMA reports that a large share of infections with herpes and trichomoniasis, and many chlamydia and gonorrhoea infections outside the genitals, cause few or no symptoms (Tuddenham et al., 2022). The same review notes that STIs are the leading cause of tubal factor infertility in women.

LML adds that it is estimated 1 in 10 sexually active young people have a chlamydia infection, and that most women do not have symptoms from the infections tested.

What the Female Sexual Health Advanced Screen checks

The Female Sexual Health - Advanced Screen combines a blood sample with a self-taken swab (or a first-catch urine sample) to look for the six most common STIs:

  • Chlamydia and gonorrhoea, by PCR on the swab or urine;
  • HIV 1 and 2, by antibody and p24 antigen in the blood;
  • Hepatitis B (surface antigen) and hepatitis C (antibody);
  • Syphilis, by antibody testing. The JAMA review notes that blood testing remains the recommended method for syphilis (Tuddenham et al., 2022).

Timing after a new partner

The NHS says STIs can take up to 7 weeks after unprotected sex to show up on a test, and that without symptoms it is best to wait 7 weeks before testing (NHS, STIs). If you have symptoms, or a partner does, do not wait: the NHS advises going to a sexual health clinic.

HPV and cervical screening

Human papillomavirus (HPV) is very common and usually clears on its own. Persistent infection with certain high-risk types is behind almost all cervical cancers, according to a 2023 JAMA review, which also describes HPV testing as about 90% sensitive for detecting cervical precancer (Perkins et al., 2023).

In England, the NHS invites women aged 25 to 64 for cervical screening every 5 years, and everyone with a cervix should be offered it (NHS, Cervical screening). NHS screening looks for high-risk HPV first. If you are in that age group, keeping up with your NHS invitation is the main route.

The HPV test in the BPR catalogue

The HPV (HR mRNA types 16, 18 + others) test looks for messenger RNA from high-risk HPV types, including 16 and 18. A 2022 systematic review found that a widely used HPV mRNA test was about as sensitive as standard HPV DNA tests on samples taken by a clinician, and less sensitive on self-collected samples (Arbyn et al., 2022). LML notes that this test is usually carried out together with a cervical smear and uses a cervical sample in a dedicated liquid vial, with results three days after the sample reaches the laboratory.

Because this is a cervical sample rather than blood or urine, it is not collected in the same way as the other tests here. Talk to us before ordering so we can confirm with LML how the sample would be taken in your case. It does not replace your NHS screening invitation.

When does testing usually make sense?

  • Before or at the start of a new relationship.
  • After a new partner, allowing the window period above.
  • At regular intervals if you have more than one partner.
  • If a partner tells you they have an infection.

As a general guide, many women test once a year or with each new partner. Talk to a health professional about what fits your situation.

How collection works

Collection is always arranged through LML, the laboratory BPR Clinic works with. Depending on the test, you can use a home kit, visit an LML collection point (you search by postcode) or book a phlebotomist to come to your home. BPR Clinic does not take samples itself. For the Advanced Screen, you take the swab yourself and the blood sample is collected with the kit, at an LML collection point or by a home phlebotomist. LML reports results one day after the samples arrive and can send a doctor's report the next day if required.

Results are confidential. If anything is positive, LML's doctor's report and your GP or a sexual health clinic can guide the next steps, including partner notification and treatment.

If you are unsure which test fits your situation, write to [email protected], use the form on our website or send a message through the app. We will help you choose, and we will always suggest you share the results with your doctor.

Frequently asked questions

I feel fine. Is there any point in testing? Yes, if you have had a new partner or unprotected sex. The NHS notes that many STIs have no symptoms and that testing is the only way to know.

How soon after sex should I test? Without symptoms, the NHS suggests waiting 7 weeks for the most reliable result. With symptoms, seek care straight away.

Does the HPV test replace my smear? No. The NHS cervical screening programme remains the main route for women aged 25 to 64. The HPV test in the catalogue is usually done together with a smear.

References

  1. Tuddenham S, Hamill MM, Ghanem KG. JAMA. 2022;327(2):161-172. PMID 35015033
  2. Perkins RB, Wentzensen N, Guido RS, Schiffman M. JAMA. 2023;330(6):547-558. PMID 37552298
  3. Arbyn M, Simon M, de Sanjosé S, et al. Lancet Oncol. 2022;23(7):950-960. PMID 35709810
  4. Sexually transmitted infections (STIs) - NHS. nhs.uk
  5. Cervical screening - NHS. nhs.uk

The tests in this article

Analysed by London Medical Laboratory. Choose a home kit, an LML collection point or a phlebotomist at home.

  • Female Sexual Health - Advanced Screen

    From £204.00

    See the test
  • HPV (HR mRNA types 16, 18 + others)

    Coming soon

    See the test

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This article is for general information and education only and is not a substitute for an individual assessment or treatment by a qualified healthcare professional. If you have significant, worsening or concerning symptoms, please seek advice from a suitably qualified clinician.