Blood tests for men from 60
After 60, high cholesterol, kidney changes and low B12 become more common, often without symptoms. A blood test shows your numbers for you and a doctor you trust.

Watch: the why in a minute
Men 60 and over
1 minute 5 seconds
Why it makes sense at this stage
What the research supports, with the source of each point at the bottom of the page.
- 01
The NHS Health Check runs to 74, and men over 50 are more likely to have high cholesterol
Every 5 years the NHS offers a cholesterol test, and possibly a blood sugar test, looking at heart disease, stroke, type 2 diabetes and kidney disease. High cholesterol gives no symptoms.[1, 2]
- 02
Low B12 becomes more common after 65
In 3,511 people in the UK aged 65 or over, it went from about 1 in 20 at 65 to 74 to 1 in 10 or more from 75. Metformin and acid reflux tablets can lower it.[3, 4]
- 03
Early kidney disease gives no warning
There are usually no symptoms in the early stages. It is linked to getting older, high blood pressure and diabetes.[5]
- 04
PSA is a choice to make with a doctor you trust, not a routine test
Routine PSA testing is not offered on the NHS, but you can ask your GP. In large trials, PSA screening made at most a small difference to prostate cancer deaths over 10 years, did not change overall deaths, and has harms to weigh.[6, 7]
- 05
Being fit does not switch off heart risk
The NHS suggests at least 150 minutes of moderate activity a week from 65. In athletes over 35, more than 80% of sudden cardiac deaths come from disease of the heart arteries, and guidelines use cholesterol in the risk score. In a UK study, long-time male endurance athletes had more artery plaques than inactive men (44.3% against 22.2%), mostly calcified; what that means is still uncertain.[8, 9, 10]
The tests and why
What usually makes sense for this group. A doctor you trust can tell you what fits your own case.
Cholesterol profile
Men over 50 are more likely to have high cholesterol, and it gives no symptoms.[1, 2]
When to repeat: Every 5 years at the NHS Health Check up to 74, or as a doctor you trust advises.
HbA1c (average blood sugar)
Blood sugar can be part of the NHS Health Check. Type 2 diabetes does not always cause symptoms.[1, 11]
When to repeat: Every 5 years at the NHS Health Check, or as a doctor you trust advises.
Kidney function (creatinine, eGFR)
Early kidney disease usually has no symptoms and is linked to getting older.[5]
When to repeat: With your cholesterol; more often with high blood pressure or diabetes.
Vitamin B12 and folate
Low B12 becomes more common after 65, and metformin and acid reflux tablets can lower it.[3, 4]
When to repeat: As a doctor you trust advises; more often on metformin or reflux tablets.
Full blood count and ferritin
Shows anaemia, which can come from low iron or low B12.[3, 12]
When to repeat: With your B12.
Vitamin D, 25(OH)D
The NHS suggests vitamin D all year for people who are not often outdoors.[13]
When to repeat: Once in late winter.
TSH and free T4 (thyroid)
Thyroid problems become more common with age.[14]
When to repeat: If you have symptoms, or as a doctor you trust advises.
What a blood test can and cannot do
It can
- Show your B12, which some common medicines lower
- Show your cholesterol, blood sugar and kidneys, which give no early symptoms
- Give you numbers to talk through with a doctor you trust
It cannot
- Turn PSA into a routine check: it is a choice with a doctor you trust
- Clear you to train or assess your heart: it shows risk factors
- Promise energy, strength or sex drive from a testosterone result
Tests that cover these markers
Not sure which one? The guided check-up suggests a starting point in a few questions.
Find your check-up
Well Man Premier Plus Profile
One test for all of it: cholesterol, HbA1c, kidneys, liver, blood count, ferritin, thyroid, vitamin D, B12, folate and testosterone. It has no PSA. It needs a blood sample from a vein, at a collection point.
Collection pointResult in about 1 working daySee the test
Well Person Premier Plus Profile
Without vitamin D, B12 or testosterone; add the vitamins below. It needs a blood sample from a vein, at a collection point.
Collection pointResult in about 1 working daySee the test
General Health Profile
Home kit with full cholesterol, HbA1c, kidneys and liver. It has no blood count; add vitamins and thyroid below.
Home kitCollection pointResult in about 1 working daySee the test
Vitamins D, B12 and folate
Vitamin D, B12 and folate together.
Home kitCollection pointResult in about 1 working daySee the test
Thyroid Check
TSH and free T4: how your thyroid is working.
Home kitCollection pointResult in about 1 working daySee the test
Testosterone Plus
Total and free testosterone with SHBG and albumin, if you have symptoms.
Home kitCollection pointResult in about 1 working daySee the test
Prices are in the app, once you have an account.
What to do with your result
Your result arrives in your account, with reference ranges. A value outside the range, or a symptom with a normal result, is a conversation with a doctor you trust: treatment and supplements are their call. Repeat the same test later to compare.
Take the guide with you
The reasons, the tests and every reference, in a few pages. Free to download, no email needed.
See also
References
- 1.NHS. NHS Health Check. nhs.uk. 2026. www.nhs.uk/tests-and-treatments/nhs-health-check/
- 2.NHS. High cholesterol. nhs.uk. 2026. www.nhs.uk/conditions/high-cholesterol/
- 3.Clarke R, Grimley Evans J, Schneede J, et al. Vitamin B12 and folate deficiency in later life. Age Ageing. 2004;33:34-41. doi:10.1093/ageing/afg109 PMID 14695861.
- 4.NHS. Vitamin B12 or folate deficiency anaemia: causes. nhs.uk. 2026. www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/causes/
- 5.NHS. Chronic kidney disease. nhs.uk. 2026. www.nhs.uk/conditions/kidney-disease/
- 6.NHS. PSA test. nhs.uk. 2026. www.nhs.uk/tests-and-treatments/psa-test/
- 7.Ilic D, Djulbegovic M, Jung JH, et al. Prostate cancer screening with prostate-specific antigen (PSA) test: a systematic review and meta-analysis. BMJ. 2018;362:k3519. doi:10.1136/bmj.k3519 PMID 30185521.
- 8.NHS. Physical activity guidelines for older adults. nhs.uk. 2026. www.nhs.uk/live-well/exercise/physical-activity-guidelines-older-adults/
- 9.Pelliccia A, Sharma S, Gati S, et al. 2020 ESC Guidelines on sports cardiology and exercise in patients with cardiovascular disease. Eur Heart J. 2021;42:17-96. doi:10.1093/eurheartj/ehaa605 PMID 32860412.
- 10.Merghani A, Maestrini V, Rosmini S, et al. Prevalence of Subclinical Coronary Artery Disease in Masters Endurance Athletes With a Low Atherosclerotic Risk Profile. Circulation. 2017;136:126-137. doi:10.1161/CIRCULATIONAHA.116.026964 PMID 28465287.
- 11.NHS. Type 2 diabetes: symptoms. nhs.uk. 2026. www.nhs.uk/conditions/type-2-diabetes/symptoms/
- 12.NHS. Iron deficiency anaemia. nhs.uk. 2026. www.nhs.uk/conditions/iron-deficiency-anaemia/
- 13.NHS. Vitamin D. nhs.uk. 2026. www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/
- 14.Vanderpump MP, Tunbridge WM, French JM, et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin Endocrinol (Oxf). 1995;43:55-68. doi:10.1111/j.1365-2265.1995.tb01894.x PMID 7641412.
- 15.Feldman HA, Longcope C, Derby CA, et al. Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study. J Clin Endocrinol Metab. 2002;87:589-598. doi:10.1210/jcem.87.2.8201 PMID 11836290.
- 16.Wu FC, Tajar A, Beynon JM, et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med. 2010;363:123-135. doi:10.1056/NEJMoa0911101 PMID 20554979.
General information, not personal medical advice. Talk to a doctor you trust, such as your GP, about your own situation. Questions: write to [email protected] or message us in the app.