Blood tests from 60: kidneys, B12, vitamin D and the heart

Blood tests from 60: kidneys, B12, vitamin D and the heart

Image for illustrative purposes only
BPR Clinic29 October 20269 min readLer em português

After 60, a few blood tests tell you more than they did at 40. What a check-up from 60 usually covers, what each marker means and what to take to your GP.

Tests in this article:General Health Profile,Kidney function (no electrolytes),Vitamin B12,Vitamin D,Cholesterol Profile,Diabetes (HbA1c),Thyroid Monitoring,Full Blood Count (with 5 part White Cell Differential)

"My GP checks my blood pressure every year. Do I need anything else?" It is one of the questions we hear most often from people in their sixties and seventies. The honest answer depends on your health, your medicines and what has already been checked. Still, a handful of blood tests from 60 tend to tell you more than they did at 40, and knowing what each one measures makes the next conversation with your GP easier. This guide covers the usual ones, in plain words.

Why blood tests from 60 look a little different

Several things change quietly with age. The kidneys filter a little less each decade, the stomach absorbs vitamin B12 less well, the skin makes less vitamin D and the chance of heart disease and type 2 diabetes keeps climbing. Many of these changes give no symptoms for years. The NHS notes that chronic kidney disease, for example, is often only found when a routine blood or urine test done for another reason shows the kidneys may not be working normally.

Medicines add another layer. After 60, more people take something every day, and some common medicines change blood results or need regular tests to keep them safe. That monitoring is arranged by whoever prescribes the medicine. A check-up you choose yourself sits alongside it, never in place of it.

Kidneys: how well they filter

The main blood test for the kidneys measures creatinine, a waste product made by your muscles. From that level, together with your age and sex, the laboratory works out an estimated glomerular filtration rate (eGFR): a figure for how well your kidneys are filtering the blood (NHS).

A doctor measuring an older man's blood pressure

The NHS recommends regular kidney testing for people with high blood pressure, diabetes or heart disease, and for people on long-term medicines that can affect the kidneys, such as lithium, omeprazole or anti-inflammatory painkillers. A urine test often goes with the blood test, so a single eGFR is only part of the picture.

Vitamin B12 and folate

Low vitamin B12 becomes more common with age, mostly because the body absorbs less of it from food, and it can build up slowly over years (Green et al., 2017). The NHS names pernicious anaemia, an autoimmune condition of the stomach, as the most common cause in the UK, and notes that it is more common in women around 60. Some everyday medicines can lower B12 too, including metformin and the acid reflux tablets known as proton pump inhibitors.

The signs are often vague: tiredness, pins and needles, a sore tongue, changes in memory or mood. That is why B12 is often part of a check-up from 60, usually together with folate, the vitamin that works alongside it to make healthy red blood cells.

Vitamin D through UK winters

From October to early March, the UK sun is not strong enough for the skin to make vitamin D. The NHS advises everyone to consider a daily 10 microgram supplement in autumn and winter, and all year round for people who are rarely outdoors, for example if they are frail, housebound or living in a care home. A blood test shows where your level stands, which can be useful if you have bone or muscle aches or have spent a lot of time indoors.

An older woman rolling out an exercise mat at home

Heart and blood sugar

If you are between 40 and 74 and do not already have heart disease, kidney disease, diabetes or high blood pressure, you should be invited to an NHS Health Check every 5 years. It includes a cholesterol test and possibly a blood sugar test, and if you are over 65 you are also told about signs of dementia to look out for (NHS).

After 74, or in the years between invitations, the two tests people most often add are a cholesterol profile and HbA1c (glycated haemoglobin), which reflects your average blood sugar over the past 2 to 3 months. You can read more about what the Health Check covers in our article on check-ups from 40.

Thyroid and full blood count

An underactive thyroid tends to start slowly, with tiredness, feeling the cold, weight gain, constipation or low mood: all easy to put down to getting older (NHS). The usual first test measures thyroid stimulating hormone (TSH) and free thyroxine (free T4).

A full blood count (FBC) looks at your red cells, white cells and platelets. It is the test the NHS uses first to check for anaemia, which can come from low iron, low B12 or folate, or other causes that your GP may want to look into.

What each marker means

Watch: what each marker means

32 seconds · AI voice. They explain the words, not your result. Take your results to a doctor you trust, such as your GP.

These are the markers you are most likely to see on a check-up report from 60. The descriptions match the ones in our blood test glossary.

  • Creatinine: a waste product made by the muscles and normally filtered out by the kidneys. A high level may point to the kidneys not filtering as well; it is also used to follow kidney conditions and adjust some medicine doses. More on creatinine.
  • Estimated glomerular filtration rate (eGFR): shows how well the kidneys are filtering the blood and removing waste. It is calculated from blood creatinine along with age, sex and body size. More on eGFR.
  • Vitamin B12: needed to form red blood cells, repair tissue and keep nerves healthy. Low levels can bring anaemia, tiredness, weakness and nerve symptoms. More on B12.
  • Folate (vitamin B9): needed for DNA, red blood cells and cell division. Low levels are linked to tiredness, weakness, pale skin and poor concentration. More on folate.
  • Vitamin D (25-hydroxyvitamin D): helps the body absorb calcium and keep bones strong. It comes from food and supplements, or is made in the skin with sunlight; low levels can lead to weak bones and muscle weakness. More on vitamin D.
  • Total cholesterol: the total amount of cholesterol in your blood. Too much can lead to plaque building up in the arteries. You might be asked not to eat for up to 12 hours before the test. More on total cholesterol.
  • Low-density lipoprotein (LDL) cholesterol: often called "bad" cholesterol, because too much can build up in the walls of the arteries. More on LDL.
  • High-density lipoprotein (HDL) cholesterol: often called "good" cholesterol, because it takes excess cholesterol back to the liver. A low level may mean a higher risk of heart disease. More on HDL.
  • Glycated haemoglobin (HbA1c): the average amount of sugar in your blood over the past 2 to 3 months, used to check for and monitor diabetes. More on HbA1c.
  • Thyroid stimulating hormone (TSH): made by the pituitary gland to regulate the thyroid. Levels that are too high or too low can point to an underactive or overactive thyroid. More on TSH.
  • Free thyroxine (free T4): the part of the thyroid hormone thyroxine that is not bound to proteins in the blood. It helps show whether the thyroid is making too much or too little hormone. More on free T4.
  • Haemoglobin: the protein in red blood cells that carries oxygen. A low level can point to anaemia, which may bring tiredness, weakness or breathlessness. More on haemoglobin.
  • Mean cell volume (MCV): the average size of your red blood cells. Cells larger than usual can go with low B12 or folate; smaller cells can go with low iron. More on MCV.

Reference ranges vary; take your results to a doctor you trust, such as your GP.

Practical tips before your check-up

  • Write down every medicine and supplement you take, including vitamins. Biotin, found in some hair and nail supplements, can change some results.
  • If you are asked to fast for a cholesterol test, it may be for up to 12 hours. Drink water as usual unless told otherwise.
  • Ask your GP surgery which tests you have already had this year; many results are in your online GP record.
  • Never start, stop or change a medicine because of a result. Talk to your GP or pharmacist first.
  • Keep copies of your results. Comparing them over time is often more useful than any single report, as we explain in why repeating blood tests over time helps.

When to get help straight away

A blood test is not the right step for sudden or severe symptoms. Call 999 for chest pain, sudden weakness on one side of the face or body, slurred speech, severe breathlessness or confusion that comes on quickly. For urgent advice that is not an emergency, call NHS 111.

Frequently asked questions

Do I still need a check-up if my GP already tests me for a long-term condition? Your GP or specialist arranges the tests your condition and medicines need, and those come first. A check-up you choose can cover something else you want to know about, such as vitamin D. Share the results with your GP so nothing is repeated without need.

How often should these tests be repeated? There is no single interval for everyone. It depends on your health, your medicines and your earlier results, so ask your GP what makes sense for you.

Is a result outside the range a sign that something is wrong? Not necessarily. One result is a snapshot, and many things can move it, from a recent illness to a new medicine. Your GP reads it alongside your history and may suggest repeating it.

Next steps

Not sure where to start? The check-up guide has cards for women from 60 and men from 60, and the group pages go into more depth: blood tests for women from 60 and blood tests for men from 60. The test pages for general health, vitamins D, B12 and folate and thyroid function show what each test includes and how the sample is collected by our partner laboratory. For the bigger picture, start with how to choose a blood test check-up.

You can order from the app or your patient area. For any question, write to [email protected] or use the form on the site. If you work with one of our therapists, bring your results to your next session as well.

This content is for information and education only and does not replace an assessment or treatment by a qualified health professional. Always talk to your GP or a health professional for individual advice.

References

  1. Green R, Allen LH, Bjørke-Monsen AL, et al. Nat Rev Dis Primers. 2017;3:17040. PMID 28660890
  2. Vitamin B12 or folate deficiency anaemia: causes - NHS. nhs.uk
  3. Chronic kidney disease: diagnosis - NHS. nhs.uk
  4. Vitamin D - NHS. nhs.uk
  5. NHS Health Check - NHS. nhs.uk
  6. Underactive thyroid (hypothyroidism) - NHS. nhs.uk
  7. Iron deficiency anaemia - NHS. nhs.uk

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This article is for general information and education only and is not a substitute for an individual assessment or treatment by a qualified healthcare professional. If you have significant, worsening or concerning symptoms, please seek advice from a suitably qualified clinician.